Alexey Kondrashov

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Alexey S. Kondrashov is a professor at the University of Michigan in Ann Arbor, MI.

He has worked on a variety of subjects in evolutionary genetics. He is best known for the deterministic mutation hypothesis[1] explaining the maintenance of sexual reproduction [2], his work on sympatric speciation,[3] and his work on evaluating mutation rates.[4]

Originally from the Russian Federation, A.S. Kondrashov has been working in the United States since the early 1990s. His work currently focuses on measuring rate of spontaneous mutation in Drosophila. Also, he studies selection at the sequence level and protein evolution.[5]

[edit] Notes

  1. ^ Kondrashov, A.S. 1988. Deleterious mutations and the evolution of sexual reproduction. Nature 336: 435-440
  2. ^ Kondrashov AS & Crow JF. 1991. Haploidy or diploidy: which is better? Nature 351:314-315
  3. ^ Kondrashov AS & Kondrashov FA. 1999. Interactions among quantitative traits in the course of symaptric speciation. Nature 400: 351-354
  4. ^ Kondrashov AS & Houle D. 1994. Genotype-Environment interactions and the estimation of the genomci mutation-reate in Drosophila melanogaster. Proceedings of the Royal Society of London Series B-Biological Sciences 258: 221-227
  5. ^ Jordan IK, Kondrashov FA, Adzhubei IA, Wolf YI, Koonin EV, Kondrashov AS, Sunyaev S. 2005. A universal trend of amino acid gain and loss in protein evolution Nature 433: 633-638

[edit] See also

http://www.lsi.umich.edu/facultyresearch/labs/kondrashov

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