Aldose 1-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, an aldose 1-dehydrogenase (EC 1.1.1.121) is an enzyme that catalyzes the chemical reaction

D-aldose + NAD⁺ D-aldonolactone + NADH + H⁺

Thus, the two substrates of this enzyme are D-aldose and NAD⁺, whereas its 3 products are D-aldonolactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-aldose:NAD+ 1-oxidoreductase. Other names in common use include aldose dehydrogenase, and dehydrogenase, D-aldohexose.

[edit] References

• IUBMB entry for 1.1.1.121
• BRENDA references for 1.1.1.121 (Recommended.)
• PubMed references for 1.1.1.121
• PubMed Central references for 1.1.1.121
• Google Scholar references for 1.1.1.121
• Cline AL, Hu AS (1965). "The isolation of three sugar dehydrogenases from a psuedomonad". J. Biol. Chem. 240: 4488–92. PMID 5845847. 
• Cline AL, Hu AS (1965). "Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240: 4493–7. PMID 5845848. 
• Cline AL, Hu AS (1965). "Some physical properties of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240: 4498–502. PMID 5845849. 

[edit] External links

The CAS registry number for this enzyme class is 9076-61-3.

• IUBMB entry for 1.1.1.121

• KEGG entry for 1.1.1.121

• BRENDA entry for 1.1.1.121

• NiceZyme view of 1.1.1.121

• EC2PDB: PDB structures for 1.1.1.121

• PRIAM entry for 1.1.1.121

• PUMA2 entry for 1.1.1.121

• IntEnz: Integrated Enzyme entry for 1.1.1.121

• MetaCyc entry for 1.1.1.121

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047640: aldose 1-dehydrogenase

• AMIGO entry for GO code 0047640: aldose 1-dehydrogenase