Aldose-1-phosphate nucleotidyltransferase

From Wikipedia, the free encyclopedia

In enzymology, an aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37) is an enzyme that catalyzes the chemical reaction

NDP + alpha-D-aldose 1-phosphate phosphate + NDP-aldose

Thus, the two substrates of this enzyme are NDP and alpha-D-aldose 1-phosphate, whereas its two products are phosphate and NDP-aldose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase. Other names in common use include sugar-1-phosphate nucleotidyltransferase, NDPaldose phosphorylase, glucose 1-phosphate inosityltransferase, NDP sugar phosphorylase, nucleoside diphosphosugar phosphorylase, sugar phosphate nucleotidyltransferase, nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase, sugar nucleotide phosphorylase, and NDP:aldose-1-phosphate nucleotidyltransferase. This enzyme participates in nucleotide sugars metabolism.

[edit] References

• IUBMB entry for 2.7.7.37
• BRENDA references for 2.7.7.37 (Recommended.)
• PubMed references for 2.7.7.37
• PubMed Central references for 2.7.7.37
• Google Scholar references for 2.7.7.37
• CABIB E, CARMINATTI H, WOYSKOVSKY NM (1965). "PHOSPHOROLYSIS OF THE PYROPHOSPHATE BOND OF SUGAR NUCLEOTIDES. II PURIFICATION AND PROPERTIES OF THE ENZYME". J. Biol. Chem. 240: 2114–21. PMID 14299635. 

[edit] External links

The CAS registry number for this enzyme class is 9033-61-8.

• IUBMB entry for 2.7.7.37

• KEGG entry for 2.7.7.37

• BRENDA entry for 2.7.7.37

• NiceZyme view of 2.7.7.37

• EC2PDB: PDB structures for 2.7.7.37

• PRIAM entry for 2.7.7.37

• PUMA2 entry for 2.7.7.37

• IntEnz: Integrated Enzyme entry for 2.7.7.37

• MetaCyc entry for 2.7.7.37

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047347: aldose-1-phosphate nucleotidyltransferase

• AMIGO entry for GO code 0047347: aldose-1-phosphate nucleotidyltransferase