Aldicarb

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Aldicarb


IUPAC name	2-methyl-2-(methylthio)propionaldehyde O-methylcarbamoyloxime
Identifiers
CAS number	[116-06-3]
Properties
Molecular formula	C₇H₁₄N₂O₂S
Molar mass	190.27 g/mol
Density	1.195 g/cm³
Melting point	100 °C
Boiling point	Decomposes before boiling point
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Aldicarb is a carbamate insecticide with structural formula: 2-methyl-2-(methylthio)propionaldehyde O-methylcarbamoyloxime. Aldicarb is the active substance in Temik pesticide, which is effective against thrips, aphids, spider mites, lygus, fleahoppers, and leafminers but is primarily used as a nematicide.^[1] Aldicarb is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. In case of severe poisoning, the victim dies of respiratory failure.

1 Regulatory Status
2 Toxicity in mammals
3 See also
4 References

[edit] Regulatory Status

Aldicarb is approved by the USEPA for use by professional pesticide applicators on a variety of crops, including cotton, beans, and others. It is not approved for household use.^[2]

"Tres Pasitos", a mouse, rat, and roach killer that contains high concentrations of aldicarb, has been illegally imported into the United States from Mexico and other Latin American countries. The product is highly toxic to animals and people, and it should not be used. EPA

[edit] Toxicity in mammals

Aldicarb is a fast-acting cholinesterase inhibitor, causing rapid accumulation of acetylcholine at the synaptic cleft. It is widely used to study cholinergic neurotransmission in simple systems such as the nematode C. elegans.

Exposure to high amounts of aldicarb can cause weakness, blurred vision, headache, nausea, tearing, sweating, and tremors in people. Very high doses can kill people, because it can paralyze the respiratory system. EPA

It has a LD50 rating of 0.5 - 1.5 mg/kg when in liquid form and a LD50 rating of 7mg/kg when in solid form.