Alcohol oxidase

From Wikipedia, the free encyclopedia

In enzymology, an alcohol oxidase (EC 1.1.3.13) is an enzyme that catalyzes the chemical reaction

a primary alcohol + O₂ $\rightleftharpoons$ an aldehyde + H₂O₂

Thus, the two substrates of this enzyme are primary alcohol and O₂, whereas its two products are aldehyde and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is alcohol:oxygen oxidoreductase. This enzyme is also called ethanol oxidase. This enzyme participates in methane metabolism. It employs one cofactor, FAD.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes 1AHU, 1AHV, 1AHZ, 1VAO, 1W1J, 1W1K, 1W1L, 1W1M, and 2VAO.

[edit] References

IUBMB entry for 1.1.3.13
BRENDA references for 1.1.3.13 (Recommended.)
PubMed references for 1.1.3.13
PubMed Central references for 1.1.3.13
Google Scholar references for 1.1.3.13
Janssen FW, Ruelius HW (1968). "Alcohol oxidase, a flavoprotein from several Basidiomycetes species Crystallization by fractional precipitation with polyethylene glycol". Biochim. Biophys. Acta. 151: 330–42. PMID 5636370.
Nishida A, Ishihara T and Hiroi T (1987). "Studies on enzymes related to lignan biodegradation". Baiomasu Henkan Keikaku Kenkyu Hokoku: 38–59.
Suye S (1997). "Purification and properties of alcohol oxidase from Candida methanosorbosa M-2003". Curr. Microbiol. 34: 374–7. PMID 9142745.