Alcohol dehydrogenase (NAD(P)+)

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In enzymology, an alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) is an enzyme that catalyzes the chemical reaction

an alcohol + NAD(P)+ an aldehyde + NAD(P)H + H⁺

The 3 substrates of this enzyme are alcohol, NAD⁺, and NADP⁺, whereas its 4 products are aldehyde, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is alcohol:NAD(P)+ oxidoreductase. Other names in common use include retinal reductase, aldehyde reductase (NADPH/NADH), and alcohol dehydrogenase [NAD(P)]. This enzyme participates in glycolysis and gluconeogenesis.

[edit] References

• IUBMB entry for 1.1.1.71
• BRENDA references for 1.1.1.71 (Recommended.)
• PubMed references for 1.1.1.71
• PubMed Central references for 1.1.1.71
• Google Scholar references for 1.1.1.71
• Fidge NH, Goodman DS (1968). "The enzymatic reducation of retinal to retinol in rat intestine". J. Biol. Chem. 243: 4372–9. PMID 4300551. 

[edit] External links

The CAS registry number for this enzyme class is 37250-10-5.

• IUBMB entry for 1.1.1.71

• KEGG entry for 1.1.1.71

• BRENDA entry for 1.1.1.71

• NiceZyme view of 1.1.1.71

• EC2PDB: PDB structures for 1.1.1.71

• PRIAM entry for 1.1.1.71

• PUMA2 entry for 1.1.1.71

• IntEnz: Integrated Enzyme entry for 1.1.1.71

• MetaCyc entry for 1.1.1.71

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018455: alcohol dehydrogenase [NAD(P)+]

• AMIGO entry for GO code 0018455: alcohol dehydrogenase [NAD(P)+]