AIM1

From Wikipedia, the free encyclopedia

Absent in melanoma 1

PDB rendering based on 2dad.

Available structures: 2dad

Identifiers

Symbol(s)

AIM1; ST4

External IDs

OMIM: 601797 MGI: 109544 HomoloGene: 18168

Gene ontology
Molecular Function:	• molecular_function • sugar binding
Cellular Component:	• cellular_component
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_001624 (mRNA)
NP_001615 (protein)

XM_001000734 (mRNA)
XP_001000734 (protein)

Location

Chr 6: 107.07 - 107.13 Mb

Chr 10: 43.64 - 43.69 Mb

Pubmed search

[1]

[2]

Absent in melanoma 1, also known as AIM1, is a human gene.^[1]

[edit] References

^ Entrez Gene: AIM1 absent in melanoma 1.

[edit] Further reading

Millikin D, Meese E, Vogelstein B, et al. (1991). "Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma.". Cancer Res. 51 (20): 5449–53. PMID 1680551.
Ray ME, Su YA, Meltzer PS, Trent JM (1996). "Isolation and characterization of genes associated with chromosome-6 mediated tumor suppression in human malignant melanoma.". Oncogene 12 (12): 2527–33. PMID 8700511.
Ray ME, Wistow G, Su YA, et al. (1997). "AIM1, a novel non-lens member of the betagamma-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma.". Proc. Natl. Acad. Sci. U.S.A. 94 (7): 3229–34. PMID 9096375.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Rajini B, Graham C, Wistow G, Sharma Y (2003). "Stability, homodimerization, and calcium-binding properties of a single, variant betagamma-crystallin domain of the protein absent in melanoma 1 (AIM1).". Biochemistry 42 (15): 4552–9. doi:10.1021/bi027384l. PMID 12693952.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Aravind P, Rajini B, Sharma Y, Sankaranarayanan R (2006). "Crystallization and preliminary X-ray crystallographic investigations on a betagamma-crystallin domain of absent in melanoma 1 (AIM1), a protein from Homo sapiens.". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62 (Pt 3): 282–4. doi:10.1107/S1744309106005380. PMID 16511323.