AGR2

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Anterior gradient homolog 2 (Xenopus laevis)
Identifiers
Symbol(s) AGR2; AG2; GOB-4; HAG-2; XAG-2
External IDs OMIM: 606358 MGI1344405 HomoloGene4674
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 10551 23795
Ensembl ENSG00000106541 ENSMUSG00000020581
Uniprot O95994 O88312
Refseq NM_006408 (mRNA)
NP_006399 (protein)
NM_011783 (mRNA)
NP_035913 (protein)
Location Chr 7: 16.8 - 16.81 Mb Chr 12: 36.5 - 36.51 Mb
Pubmed search [1] [2]

Anterior gradient homolog 2 (Xenopus laevis), also known as AGR2, is a human gene.[1]


[edit] References

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Thompson DA, Weigel RJ (1998). "hAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines.". Biochem. Biophys. Res. Commun. 251 (1): 111-6. doi:10.1006/bbrc.1998.9440. PMID 9790916. 
  • Petek E, Windpassinger C, Egger H, et al. (2000). "Localization of the human anterior gradient-2 gene (AGR2) to chromosome band 7p21.3 by radiation hybrid mapping and fluorescencein situ hybridisation.". Cytogenet. Cell Genet. 89 (3-4): 141-2. PMID 10965104. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Fletcher GC, Patel S, Tyson K, et al. (2003). "hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.". Br. J. Cancer 88 (4): 579-85. doi:10.1038/sj.bjc.6600740. PMID 12592373. 
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205. 
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819-24. doi:10.1110/ps.04682504. PMID 15340161. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Zhang JS, Gong A, Cheville JC, et al. (2005). "AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer.". Genes Chromosomes Cancer 43 (3): 249-59. doi:10.1002/gcc.20188. PMID 15834940. 
  • Persson S, Rosenquist M, Knoblach B, et al. (2005). "Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family.". Mol. Phylogenet. Evol. 36 (3): 734-40. doi:10.1016/j.ympev.2005.04.002. PMID 15935701. 
  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957-68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Fritzsche FR, Dahl E, Pahl S, et al. (2006). "Prognostic relevance of AGR2 expression in breast cancer.". Clin. Cancer Res. 12 (6): 1728-34. doi:10.1158/1078-0432.CCR-05-2057. PMID 16551856. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Zhang Y, Forootan SS, Liu D, et al. (2007). "Increased expression of anterior gradient-2 is significantly associated with poor survival of prostate cancer patients.". Prostate Cancer Prostatic Dis. 10 (3): 293-300. doi:10.1038/sj.pcan.4500960. PMID 17457305.