AGMAT

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It has been suggested that this article or section be merged with Agmatinase. (Discuss)

Agmatine ureohydrolase (agmatinase)

Identifiers

Symbol(s)

AGMAT; FLJ23384

External IDs

MGI: 1923236 HomoloGene: 11699

Gene ontology
Molecular Function:	• arginase activity • agmatinase activity • hydrolase activity • manganese ion binding • metal ion binding
Cellular Component:	• mitochondrion
Biological Process:	• arginine catabolic process • spermidine biosynthetic process • putrescine biosynthetic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_024758 (mRNA)
NP_079034 (protein)

XM_915401 (mRNA)
XP_920494 (protein)

Location

Chr 1: 15.77 - 15.78 Mb

Chr 4: 141.02 - 141.03 Mb

Pubmed search

[1]

[2]

Agmatine ureohydrolase (agmatinase), also known as AGMAT, is a human gene.^[1]

[edit] References

^ Entrez Gene: AGMAT agmatine ureohydrolase (agmatinase).

[edit] Further reading

Morris SM (2004). "Vertebrate agmatinases: what role do they play in agmatine catabolism?". Ann. N. Y. Acad. Sci. 1009: 30-3. PMID 15028567.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Chen FW, Davies JP, Ioannou YA (1998). "Differential gene expression in apoptosis: identification of ribosomal protein 23K, a cell proliferation inhibitor.". Mol. Genet. Metab. 64 (4): 271-82. doi:10.1006/mgme.1998.2718. PMID 9758718.
Mistry SK, Burwell TJ, Chambers RM, et al. (2002). "Cloning of human agmatinase. An alternate path for polyamine synthesis induced in liver by hepatitis B virus.". Am. J. Physiol. Gastrointest. Liver Physiol. 282 (2): G375-81. doi:10.1152/ajpgi.00386.2001. PMID 11804860.
Iyer RK, Kim HK, Tsoa RW, et al. (2002). "Cloning and characterization of human agmatinase.". Mol. Genet. Metab. 75 (3): 209-18. doi:10.1006/mgme.2001.3277. PMID 11914032.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Dallmann K, Junker H, Balabanov S, et al. (2004). "Human agmatinase is diminished in the clear cell type of renal cell carcinoma.". Int. J. Cancer 108 (3): 342-7. doi:10.1002/ijc.11459. PMID 14648699.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Kim KH, Ahn HJ, Kim DJ, et al. (2006). "Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase.". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61 (Pt 10): 889-91. doi:10.1107/S1744309105027193. PMID 16511187.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.