AGK (gene)

From Wikipedia, the free encyclopedia

Acylglycerol kinase

Identifiers

AGK; FLJ10842; MULK

External IDs

OMIM: 610345 MGI: 1917173 HomoloGene: 41239

Gene ontology
Molecular Function:	• nucleotide binding • ceramide kinase activity • diacylglycerol kinase activity • ATP binding • transferase activity • acylglycerol kinase activity
Cellular Component:	• mitochondrion • membrane
Biological Process:	• protein kinase C activation • lipid phosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018238 (mRNA)
NP_060708 (protein)

NM_023538 (mRNA)
NP_076027 (protein)

Location

Chr 7: 140.9 - 141 Mb

Chr 6: 40.26 - 40.33 Mb

Pubmed search

[1]

[2]

Acylglycerol kinase, also known as AGK, is a human gene.^[1]

[edit] References

^ Entrez Gene: AGK acylglycerol kinase.

[edit] Further reading

Spiegel S, Milstien S (2007). "Functions of the multifaceted family of sphingosine kinases and some close relatives.". J. Biol. Chem. 282 (4): 2125-9. doi:10.1074/jbc.R600028200. PMID 17135245.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Waggoner DW, Johnson LB, Mann PC, et al. (2004). "MuLK, a eukaryotic multi-substrate lipid kinase.". J. Biol. Chem. 279 (37): 38228-35. doi:10.1074/jbc.M405932200. PMID 15252046.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Bektas M, Payne SG, Liu H, et al. (2005). "A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells.". J. Cell Biol. 169 (5): 801-11. doi:10.1083/jcb.200407123. PMID 15939762.
Van Overloop H, Gijsbers S, Van Veldhoven PP (2006). "Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies.". J. Lipid Res. 47 (2): 268-83. doi:10.1194/jlr.M500321-JLR200. PMID 16269826.