Adenylyl-sulfate reductase

From Wikipedia, the free encyclopedia

In enzymology, an adenylyl-sulfate reductase (EC 1.8.99.2) is an enzyme that catalyzes the chemical reaction

AMP + sulfite + acceptor \rightleftharpoons adenylyl sulfate + reduced acceptor

The 3 substrates of this enzyme are AMP, sulfite, and acceptor, whereas its two products are adenylyl sulfate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with other acceptors. The systematic name of this enzyme class is AMP,sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming). Other names in common use include adenosine phosphosulfate reductase, adenosine 5'-phosphosulfate reductase, APS-reductase, APS reductase, AMP, sulfite:(acceptor) oxidoreductase, and (adenosine-5'-phosphosulfate-forming). This enzyme participates in selenoamino acid metabolism and sulfur metabolism. It has 2 cofactors: FAD, and Iron.

Contents

[edit] Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1JNR, 1JNZ, 2FJA, 2FJB, 2FJD, and 2FJE.

[edit] References

[edit] External links

The CAS registry number for this enzyme class is 9027-75-2.

[edit] Gene Ontology (GO) codes

 This EC 1.8 enzyme-related article is a stub. You can help Wikipedia by expanding it.