Adenosine-phosphate deaminase

From Wikipedia, the free encyclopedia

In enzymology, an adenosine-phosphate deaminase (EC 3.5.4.17) is an enzyme that catalyzes the chemical reaction

5'-AMP + H₂O 5'-IMP + NH₃

Thus, the two substrates of this enzyme are 5'-AMP and H₂O, whereas its two products are 5'-IMP and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is adenosine-phosphate aminohydrolase. Other names in common use include adenylate deaminase, adenine nucleotide deaminase, and adenosine (phosphate) deaminase.

[edit] References

• IUBMB entry for 3.5.4.17
• BRENDA references for 3.5.4.17 (Recommended.)
• PubMed references for 3.5.4.17
• PubMed Central references for 3.5.4.17
• Google Scholar references for 3.5.4.17
• Su JC, Li CC, Ting CC (1966). "A new adenylate deaminase from red marine alga Porphyra crispata". Biochemistry. 5: 536–43. PMID 5940938. 
• Yates MG (1969). "A non-specific adenine nucleotide deaminase from desulfovibrio desulfuricans". Biochim. Biophys. Acta. 171: 299–310. PMID 5773435. 

[edit] External links

The CAS registry number for this enzyme class is 37289-20-6.

• IUBMB entry for 3.5.4.17

• KEGG entry for 3.5.4.17

• BRENDA entry for 3.5.4.17

• NiceZyme view of 3.5.4.17

• EC2PDB: PDB structures for 3.5.4.17

• PRIAM entry for 3.5.4.17

• PUMA2 entry for 3.5.4.17

• IntEnz: Integrated Enzyme entry for 3.5.4.17

• MetaCyc entry for 3.5.4.17

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047623: adenosine-phosphate deaminase

• AMIGO entry for GO code 0047623: adenosine-phosphate deaminase