Adenophostin

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Adenophostin A
IUPAC name [(2R,3R,4R,5R)-2-(6-Amino-9-purinyl)-4-[[(2R,3R,4R,5R,6R)-3-hydroxy-6-(hydroxymethyl)-4,5-diphosphonooxy-2-tetrahydropyranyl]oxy]-5-(hydroxymethyl)-3-tetrahydrofuranyl] dihydrogen phosphate
Identifiers
CAS number
PubChem 123695
SMILES C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)OP(=O)(O)O)OP(=O)(O)O)O)OP(=O)(O)O
Properties
Molecular formula C16H26N5O18P3
Molar mass 669.321623
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Adenophostin is a potent inositol triphosphate (IP3) receptor agonist, but is much more potent than IP3.

IPR3 is a ligand-gated intracellular Ca2+ release channel that plays a central role in modulating cytoplasmic free Ca2+ concentration (Ca2+i). Adenophostin A is structurally different from IP3 but could elicit distinct calcium signals in cells.

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