Acylpyruvate hydrolase

From Wikipedia, the free encyclopedia

In enzymology, an acylpyruvate hydrolase (EC 3.7.1.5) is an enzyme that catalyzes the chemical reaction

a 3-acylpyruvate + H₂O a carboxylate + pyruvate

Thus, the two substrates of this enzyme are 3-acylpyruvate and water, whereas its two products are carboxylate and pyruvate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 3-acylpyruvate acylhydrolase. This enzyme participates in tyrosine metabolism.

[edit] References

• IUBMB entry for 3.7.1.5
• BRENDA references for 3.7.1.5 (Recommended.)
• PubMed references for 3.7.1.5
• PubMed Central references for 3.7.1.5
• Google Scholar references for 3.7.1.5
• Watson GK, Houghton C, Cain RB (1974). "Microbial metabolism of the pyridine ring. The metabolism of pyridine-3,4-diol (3,4-dihydroxypyridine) by Agrobacterium sp". Biochem. J. 140: 277–92. PMID 4375963. 

[edit] External links

The CAS registry number for this enzyme class is 54004-67-0.

• IUBMB entry for 3.7.1.5

• KEGG entry for 3.7.1.5

• BRENDA entry for 3.7.1.5

• NiceZyme view of 3.7.1.5

• EC2PDB: PDB structures for 3.7.1.5

• PRIAM entry for 3.7.1.5

• PUMA2 entry for 3.7.1.5

• IntEnz: Integrated Enzyme entry for 3.7.1.5

• MetaCyc entry for 3.7.1.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047621: acylpyruvate hydrolase

• AMIGO entry for GO code 0047621: acylpyruvate hydrolase