Acylglycerol kinase

From Wikipedia, the free encyclopedia

In enzymology, an acylglycerol kinase (EC 2.7.1.94) is an enzyme that catalyzes the chemical reaction

ATP + acylglycerol ADP + acyl-sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are ATP and acylglycerol, whereas its two products are ADP and acyl-sn-glycerol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:acylglycerol 3-phosphotransferase. Other names in common use include monoacylglycerol kinase, monoacylglycerol kinase (phosphorylating), sn-2-monoacylglycerol kinase, MGK, monoglyceride kinase, and monoglyceride phosphokinase. This enzyme participates in glycerolipid metabolism.

[edit] References

• IUBMB entry for 2.7.1.94
• BRENDA references for 2.7.1.94 (Recommended.)
• PubMed references for 2.7.1.94
• PubMed Central references for 2.7.1.94
• Google Scholar references for 2.7.1.94
• PIERINGER RA, HOKIN LE (1962). "Biosynthesis of lysophosphatdic acid from monoglyceride and adenosine triphosphate". J. Biol. Chem. 237: 653–8. PMID 14486486. 
• Pieringer RA and Kunnes RS (1965). "The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in Escherichia coli". J. Biol. Chem. 240: 2833–2838. 

[edit] External links

The CAS registry number for this enzyme class is 62213-37-0.

• IUBMB entry for 2.7.1.94

• KEGG entry for 2.7.1.94

• BRENDA entry for 2.7.1.94

• NiceZyme view of 2.7.1.94

• EC2PDB: PDB structures for 2.7.1.94

• PRIAM entry for 2.7.1.94

• PUMA2 entry for 2.7.1.94

• IntEnz: Integrated Enzyme entry for 2.7.1.94

• MetaCyc entry for 2.7.1.94

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047620: acylglycerol kinase

• AMIGO entry for GO code 0047620: acylglycerol kinase