ACP6

From Wikipedia, the free encyclopedia

Acid phosphatase 6, lysophosphatidic

Identifiers

ACP6; LPAP; ACPL1; PACPL1

External IDs

MGI: 1931010 HomoloGene: 41128

Gene ontology
Molecular Function:	• acid phosphatase activity • hydrolase activity
Cellular Component:	• mitochondrion
Biological Process:	• lipid metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_016361 (mRNA)
NP_057445 (protein)

NM_019800 (mRNA)
NP_062774 (protein)

Location

Chr 1: 145.59 - 145.61 Mb

Chr 3: 97.24 - 97.26 Mb

Pubmed search

[1]

[2]

Acid phosphatase 6, lysophosphatidic, also known as ACP6, is a human gene.^[1]

[edit] References

^ Entrez Gene: ACP6 acid phosphatase 6, lysophosphatidic.

[edit] Further reading

Hiroyama M, Takenawa T (1999). "Purification and characterization of a lysophosphatidic acid-specific phosphatase.". Biochem. J. 336 ( Pt 2): 483–9. PMID 9820827.
Hiroyama M, Takenawa T (1999). "Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis.". J. Biol. Chem. 274 (41): 29172–80. PMID 10506173.
Takayama I, Daigo Y, Ward SM, et al. (2002). "Novel human and mouse genes encoding an acid phosphatase family member and its downregulation in W/W(V) mouse jejunum.". Gut 50 (6): 790–6. PMID 12010880.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Tanaka M, Kishi Y, Takanezawa Y, et al. (2004). "Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.". FEBS Lett. 571 (1-3): 197–204. doi:10.1016/j.febslet.2004.06.083. PMID 15280042.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.