Acidic leucine-rich nuclear phosphoprotein 32 family member A

From Wikipedia, the free encyclopedia

Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

Identifiers

ANP32A; C15orf1; I1PP2A; LANP; MAPM; MGC119787; MGC150373; PHAP1; PHAPI; PP32

External IDs

OMIM: 600832 MGI: 108447 HomoloGene: 21269

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• nucleus • cytoplasm • endoplasmic reticulum • perinuclear region of cytoplasm
Biological Process:	• nucleocytoplasmic transport • intracellular signaling cascade

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006305 (mRNA)
NP_006296 (protein)

NM_009672 (mRNA)
NP_033802 (protein)

Location

Chr 15: 66.85 - 66.9 Mb

Chr 9: 62.17 - 62.18 Mb

Pubmed search

[1]

[2]

Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A, also known as ANP32A, is a human gene.^[1]

[edit] References

^ Entrez Gene: ANP32A Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A.

[edit] Further reading

Matilla A, Radrizzani M (2005). "The Anp32 family of proteins containing leucine-rich repeats.". Cerebellum 4 (1): 7–18. PMID 15895553.
Schraven B, Kirchgessner H, Gaber B, et al. (1991). "A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate.". Eur. J. Immunol. 21 (10): 2469–77. PMID 1655467.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Vaesen M, Barnikol-Watanabe S, Götz H, et al. (1994). "Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.". Biol. Chem. Hoppe-Seyler 375 (2): 113–26. PMID 8192856.
Fink TM, Vaesen M, Kratzin HD, et al. (1996). "Localization of the gene encoding the putative human HLA class II associated protein (PHAPI) to chromosome 15q22.3-q23 by fluorescence in situ hybridization.". Genomics 29 (1): 309–10. doi:10.1006/geno.1995.1257. PMID 8530098.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Li M, Makkinje A, Damuni Z (1996). "Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A.". Biochemistry 35 (22): 6998–7002. doi:10.1021/bi960581y. PMID 8679524.
Chen TH, Brody JR, Romantsev FE, et al. (1997). "Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci.". Mol. Biol. Cell 7 (12): 2045–56. PMID 8970164.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.
Ulitzur N, Humbert M, Pfeffer SR (1997). "Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules.". Proc. Natl. Acad. Sci. U.S.A. 94 (10): 5084–9. PMID 9144194.
Matilla A, Koshy BT, Cummings CJ, et al. (1997). "The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.". Nature 389 (6654): 974–8. doi:10.1038/40159. PMID 9353121.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Kadkol SS, Brody JR, Pevsner J, et al. (1999). "Modulation of oncogenic potential by alternative gene use in human prostate cancer.". Nat. Med. 5 (3): 275–9. doi:10.1038/6488. PMID 10086381.
Brody JR, Kadkol SS, Mahmoud MA, et al. (1999). "Identification of sequences required for inhibition of oncogene-mediated transformation by pp32.". J. Biol. Chem. 274 (29): 20053–5. PMID 10400610.
Brennan CM, Gallouzi IE, Steitz JA (2000). "Protein ligands to HuR modulate its interaction with target mRNAs in vivo.". J. Cell Biol. 151 (1): 1–14. PMID 11018049.
Seo SB, McNamara P, Heo S, et al. (2001). "Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein.". Cell 104 (1): 119–30. PMID 11163245.
Bai J, Brody JR, Kadkol SS, Pasternack GR (2001). "Tumor suppression and potentiation by manipulation of pp32 expression.". Oncogene 20 (17): 2153–60. doi:10.1038/sj.onc.1204294. PMID 11360199.
Beresford PJ, Zhang D, Oh DY, et al. (2001). "Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks.". J. Biol. Chem. 276 (46): 43285–93. doi:10.1074/jbc.M108137200. PMID 11555662.
Gallouzi IE, Brennan CM, Steitz JA (2001). "Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.". RNA 7 (9): 1348–61. PMID 11565755.
Gallouzi IE, Steitz JA (2001). "Delineation of mRNA export pathways by the use of cell-permeable peptides.". Science 294 (5548): 1895–901. doi:10.1126/science.1064693. PMID 11729309.