Acetylene hydratase

From Wikipedia, the free encyclopedia

In enzymology, an acetylene hydratase (EC 4.2.1.112) is an enzyme that catalyzes the chemical reaction

acetaldehyde acetylene + H₂O

Hence, this enzyme has one substrate, acetaldehyde, and two products, acetylene and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is acetaldehyde hydro-lyase (acetylene-forming). Other names in common use include AH, and acetaldehyde hydro-lyase. This enzyme participates in tetrachloroethene degradation.

[edit] References

• IUBMB entry for 4.2.1.112
• BRENDA references for 4.2.1.112 (Recommended.)
• PubMed references for 4.2.1.112
• PubMed Central references for 4.2.1.112
• Google Scholar references for 4.2.1.112
• Rosner BM, Schink B (1995). "Purification and characterization of acetylene hydratase of Pelobacter acetylenicus, a tungsten iron-sulfur protein". J. Bacteriol. 177: 5767–72. PMID 7592321. 
• Einsle O (2007). "Structure of the non-redox-active tungsten/[4Fe:4S] enzyme acetylene hydratase". Proc. Natl. Acad. Sci. U. S. A. 104: 3073–7. doi:10.1073/pnas.0610407104. PMID 17360611. 

[edit] External links

• IUBMB entry for 4.2.1.112

• KEGG entry for 4.2.1.112

• BRENDA entry for 4.2.1.112

• NiceZyme view of 4.2.1.112

• EC2PDB: PDB structures for 4.2.1.112

• PRIAM entry for 4.2.1.112

• PUMA2 entry for 4.2.1.112

• IntEnz: Integrated Enzyme entry for 4.2.1.112

• MetaCyc entry for 4.2.1.112

• Atomic-resolution structures of enzymes belonging to this class