Acetone carboxylase

From Wikipedia, the free encyclopedia

In enzymology, an acetone carboxylase (EC 6.4.1.6) is an enzyme that catalyzes the chemical reaction

acetone + CO₂ + ATP + 2 H₂O acetoacetate + AMP + 2 phosphate

The 4 substrates of this enzyme are acetone, CO₂, ATP, and H₂O, whereas its 3 products are acetoacetate, AMP, and phosphate.

This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is acetone:carbon-dioxide ligase (AMP-forming).

[edit] References

• IUBMB entry for 6.4.1.6
• BRENDA references for 6.4.1.6 (Recommended.)
• PubMed references for 6.4.1.6
• PubMed Central references for 6.4.1.6
• Google Scholar references for 6.4.1.6
• Sluis MK, Ensign SA (1997). "Purification and characterization of acetone carboxylase from Xanthobacter strain Py2". Proc. Natl. Acad. Sci. U. S. A. 94: 8456–61. PMID 9237998. 

[edit] External links

• IUBMB entry for 6.4.1.6

• KEGG entry for 6.4.1.6

• BRENDA entry for 6.4.1.6

• NiceZyme view of 6.4.1.6

• EC2PDB: PDB structures for 6.4.1.6

• PRIAM entry for 6.4.1.6

• PUMA2 entry for 6.4.1.6

• IntEnz: Integrated Enzyme entry for 6.4.1.6

• MetaCyc entry for 6.4.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018710: acetone carboxylase

• AMIGO entry for GO code 0018710: acetone carboxylase