Acetate kinase (diphosphate)

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In enzymology, an acetate kinase (diphosphate) (EC 2.7.2.12) is an enzyme that catalyzes the chemical reaction

diphosphate + acetate phosphate + acetyl phosphate

Thus, the two substrates of this enzyme are diphosphate and acetate, whereas its two products are phosphate and acetyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is diphosphate:acetate phosphotransferase. This enzyme is also called pyrophosphate-acetate phosphotransferase. This enzyme participates in pyruvate metabolism.

[edit] References

• IUBMB entry for 2.7.2.12
• BRENDA references for 2.7.2.12 (Recommended.)
• PubMed references for 2.7.2.12
• PubMed Central references for 2.7.2.12
• Google Scholar references for 2.7.2.12
• Reeves RE, Guthrie JD (1975). "Acetate kinase (pyrophosphate). A fourth pyrophosphate-dependent kinase from Entamoeba histolytica". Biochem. Biophys. Res. Commun. 66: 1389–95. doi:10.1016/0006-291X(75)90513-6. PMID 172079. 

[edit] External links

The CAS registry number for this enzyme class is 57657-58-6.

• IUBMB entry for 2.7.2.12

• KEGG entry for 2.7.2.12

• BRENDA entry for 2.7.2.12

• NiceZyme view of 2.7.2.12

• EC2PDB: PDB structures for 2.7.2.12

• PRIAM entry for 2.7.2.12

• PUMA2 entry for 2.7.2.12

• IntEnz: Integrated Enzyme entry for 2.7.2.12

• MetaCyc entry for 2.7.2.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047601: acetate kinase (diphosphate)

• AMIGO entry for GO code 0047601: acetate kinase (diphosphate)