ABHD2

From Wikipedia, the free encyclopedia

Abhydrolase domain containing 2

Identifiers

ABHD2; HS1-2; LABH2; MGC111112; MGC26249; PHPS1-2

External IDs

MGI: 1914344 HomoloGene: 23121

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• membrane • integral to membrane
Biological Process:	• biological_process • response to wounding • negative regulation of cell migration

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_007011 (mRNA)
NP_008942 (protein)

NM_018811 (mRNA)
NP_061281 (protein)

Location

Chr 15: 87.43 - 87.54 Mb

Chr 7: 79.15 - 79.24 Mb

Pubmed search

[1]

[2]

Abhydrolase domain containing 2, also known as ABHD2, is a human gene.^[1]

This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding the same protein.^[1]

[edit] References

^ ^a ^b Entrez Gene: ABHD2 abhydrolase domain containing 2.

[edit] Further reading

Miyata K, Nakayama M, Mizuta S, et al. (2007). "Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque.". Biochem. Biophys. Res. Commun. 365 (2): 207–13. doi:10.1016/j.bbrc.2007.10.127. PMID 17980156.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Edgar AJ, Polak JM (2002). "Cloning and tissue distribution of three murine alpha/beta hydrolase fold protein cDNAs.". Biochem. Biophys. Res. Commun. 292 (3): 617–25. doi:10.1006/bbrc.2002.6692. PMID 11922611.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Rapiejko PJ, George ST, Malbon CC (1988). "Primary structure of a human protein which bears structural similarities to members of the rhodopsin/beta-adrenergic receptor family.". Nucleic Acids Res. 16 (17): 8721. PMID 2843827.