90Y-DOTA-biotin
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90Y-DOTA-biotin is a radioactive substance (yttrium-90) joined by a large chemical link (DOTA) to biotin, a vitamin. It is often used in pretargeted radioimmunotherapy, especially in cancer research.
[edit] References
- Domingo RJ, Reilly RM (2000). "Pre-targeted radioimmunotherapy of human colon cancer xenografts in athymic mice using streptavidin-CC49 monoclonal antibody and 90Y-DOTA-biotin". Nuclear medicine communications 21 (1): 89–96. doi:. PMID 10717908.
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