8-oxoguanine

From Wikipedia, the free encyclopedia

The introduction to this article provides insufficient context for those unfamiliar with the subject. Please help improve the article with a good introductory style.

This article does not cite any references or sources. (February 2008) Please help improve this article by adding citations to reliable sources. Unverifiable material may be challenged and removed.

8-Oxo-7,8-dihydroguanine, also 8-oxoguanine, 8-hydroxyguanine, 8-oxo-Gua, or oh⁸Gua, is one of the most common DNA lesions resulting from reactive oxygen species. It is primarily repaired by the DNA glycosylase OGG1. It is caused by radiation in x rays and chernobyl. It is also produced in oxidative metabolism.