8-OH-DPAT

From Wikipedia, the free encyclopedia

8-OH-DPAT
Systematic (IUPAC) name
8-Hydroxy-2-(di-n-propylamino)tetralin
Identifiers
CAS number 78950-78-4
ATC code  ?
PubChem 1220
Chemical data
Formula C16H25NO 
Mol. mass 247.38 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tertraline) is a substance which acts as an agonist of the 5HT1A and 5HT7 receptors.[1]

It can elicit pelvic floor contractions [2].

[edit] References

  1. ^ S. Schuhler, M. Saboureau, B. Pitrosky and P. Pévet (October 1998). "In Syrian hamsters, 5-HT fibres within the suprachiasmatic nuclei are necessary for the expression of 8-OH-DPAT induced phase-advance of locomotor activity rhythm". Neuroscience Letters 256 (1): 33–36. doi:10.1016/S0304-3940(98)00749-6. 
  2. ^ Thomas et al., (2007)