6-phospho-beta-glucosidase

From Wikipedia, the free encyclopedia

In enzymology, a 6-phospho-beta-glucosidase (EC 3.2.1.86) is an enzyme that catalyzes the chemical reaction

6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H₂O D-glucose + D-glucose 6-phosphate

Thus, the two substrates of this enzyme are 6-phospho-beta-D-glucosyl-(1,4)-D-glucose and H₂O, whereas its two products are D-glucose and D-glucose 6-phosphate.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase. Other names in common use include phospho-beta-glucosidase A, phospho-beta-glucosidase, and phosphocellobiase. This enzyme participates in glycolysis / gluconeogenesis.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1S6Y.

[edit] References

• IUBMB entry for 3.2.1.86
• BRENDA references for 3.2.1.86 (Recommended.)
• PubMed references for 3.2.1.86
• PubMed Central references for 3.2.1.86
• Google Scholar references for 3.2.1.86
• Palmer RE, Anderson RL (1972). "Cellobiose metabolism in Aerobacter aerogenes. 3. Cleavage of cellobiose monophosphate by a phospho- -glucosidase". J. Biol. Chem. 247: 3420–3. PMID 4624114. 

[edit] External links

The CAS registry number for this enzyme class is 37205-51-9.

• IUBMB entry for 3.2.1.86

• KEGG entry for 3.2.1.86

• BRENDA entry for 3.2.1.86

• NiceZyme view of 3.2.1.86

• EC2PDB: PDB structures for 3.2.1.86

• PRIAM entry for 3.2.1.86

• PUMA2 entry for 3.2.1.86

• IntEnz: Integrated Enzyme entry for 3.2.1.86

• MetaCyc entry for 3.2.1.86

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008706: 6-phospho-beta-glucosidase

• AMIGO entry for GO code 0008706: 6-phospho-beta-glucosidase