6-phospho-beta-galactosidase

From Wikipedia, the free encyclopedia

In enzymology, a 6-phospho-beta-galactosidase (EC 3.2.1.85) is an enzyme that catalyzes the chemical reaction

a 6-phospho-beta-D-galactoside + H₂O 6-phospho-D-galactose + an alcohol

Thus, the two substrates of this enzyme are 6-phospho-beta-D-galactoside and H₂O, whereas its two products are 6-phospho-D-galactose and alcohol.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 6-phospho-beta-D-galactoside 6-phosphogalactohydrolase. Other names in common use include phospho-beta-galactosidase, beta-D-phosphogalactoside galactohydrolase, phospho-beta-D-galactosidase, and 6-phospho-beta-D-galactosidase. This enzyme participates in galactose metabolism.

[edit] Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1PBG, 2PBG, 3PBG, and 4PBG.

[edit] References

• IUBMB entry for 3.2.1.85
• BRENDA references for 3.2.1.85 (Recommended.)
• PubMed references for 3.2.1.85
• PubMed Central references for 3.2.1.85
• Google Scholar references for 3.2.1.85
• Hengstenberg W, Penberthy WK, Morse ML (1970). "Purification of the staphylococcal 6-phospho-beta-D-- galactosidase". Eur. J. Biochem. 14: 27–32. doi:10.1111/j.1432-1033.1970.tb00256.x. PMID 5447434. 

[edit] External links

The CAS registry number for this enzyme class is 37237-42-6.

• IUBMB entry for 3.2.1.85

• KEGG entry for 3.2.1.85

• BRENDA entry for 3.2.1.85

• NiceZyme view of 3.2.1.85

• EC2PDB: PDB structures for 3.2.1.85

• PRIAM entry for 3.2.1.85

• PUMA2 entry for 3.2.1.85

• IntEnz: Integrated Enzyme entry for 3.2.1.85

• MetaCyc entry for 3.2.1.85

• Atomic-resolution structures of enzymes belonging to this class