6-aminohexanoate-cyclic-dimer hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a 6-aminohexanoate-cyclic-dimer hydrolase (EC 3.5.2.12) is an enzyme that catalyzes the chemical reaction

1,8-diazacyclotetradecane-2,9-dione + H₂O N-(6-aminohexanoyl)-6-aminohexanoate

Thus, the two substrates of this enzyme are 1,8-diazacyclotetradecane-2,9-dione and H₂O, whereas its product is N-(6-aminohexanoyl)-6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase.

[edit] References

• IUBMB entry for 3.5.2.12
• BRENDA references for 3.5.2.12 (Recommended.)
• PubMed references for 3.5.2.12
• PubMed Central references for 3.5.2.12
• Google Scholar references for 3.5.2.12
• Kinoshita S, Negoro S, Muramatsu M, Bisaria VS, Sawada S, Okada H (1977). "6-Aminohexanoic acid cyclic dimer hydrolase. A new cyclic amide hydrolase produced by Achromobacter guttatus KI74". Eur. J. Biochem. 80: 489–95. doi:10.1111/j.1432-1033.1977.tb11904.x. PMID 923591. 

[edit] External links

The CAS registry number for this enzyme class is 60976-29-6.

• IUBMB entry for 3.5.2.12

• KEGG entry for 3.5.2.12

• BRENDA entry for 3.5.2.12

• NiceZyme view of 3.5.2.12

• EC2PDB: PDB structures for 3.5.2.12

• PRIAM entry for 3.5.2.12

• PUMA2 entry for 3.5.2.12

• IntEnz: Integrated Enzyme entry for 3.5.2.12

• MetaCyc entry for 3.5.2.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0019874: 6-aminohexanoate-cyclic-dimer hydrolase

• AMIGO entry for GO code 0019874: 6-aminohexanoate-cyclic-dimer hydrolase