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| 5.8S ribosomal RNA |
 |
| Type: |
Gene; rRNA; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Wuyts et al, European LSU rRNA database[1] |
| Avg length: |
153.4 nucleotides |
| Avg identity: |
78% |
|
5.8S ribosomal RNA (5.8S rRNA) is a component of the large subunit of the eukaryotic ribosome. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Functionally, it is thought that 5.8S rRNA may be involved in ribosome translocation.[2] It is also known to form covalent linkage to the p53 tumour suppressor protein.[3] 5.8S rRNA is also found in archaea.
[edit] References
- ^ Wuyts, J; De Rijk P, Van de Peer Y, Winkelmans T, De Wachter R (2001). "The European Large Subunit Ribosomal RNA Database". Nucleic Acids Res 29: 175–177. doi:10.1093/nar/29.1.175. PMID 11125083.
- ^ Abou, Elela S; Nazar RN (1997). "Role of the 5.8S rRNA in ribosome translocation". Nucleic Acids Res 25: 1788–1794. doi:10.1093/nar/25.9.1788. PMID 9108162.
- ^ Fontoura, BM; Atienza CA, Sorokina EA, Morimoto T, Carroll RB (1997). "Cytoplasmic p53 polypeptide is associated with ribosomes". Mol Cell Biol 17: 3146–3154. PMID 9154813.
[edit] External links
