5-phytase

From Wikipedia, the free encyclopedia

In enzymology, a 5-phytase (EC 3.1.3.72) is an enzyme that catalyzes the chemical reaction

myo-inositol hexakisphosphate + H₂O 1L-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate

Thus, the two substrates of this enzyme are myo-inositol hexakisphosphate and H₂O, whereas its two products are 1L-myo-inositol 1,2,3,4,6-pentakisphosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is myo-inositol-hexakisphosphate 5-phosphohydrolase.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1U24, 1U25, 1U26, 2B4O, 2B4P, and 2B4U.

[edit] References

• IUBMB entry for 3.1.3.72
• BRENDA references for 3.1.3.72 (Recommended.)
• PubMed references for 3.1.3.72
• PubMed Central references for 3.1.3.72
• Google Scholar references for 3.1.3.72
• Barrientos L, Scott JJ, Murthy PP (1994). "Specificity of hydrolysis of phytic acid by alkaline phytase from lily pollen". Plant. Physiol. 106: 1489–95. PMID 7846160. 

[edit] External links

The CAS registry number for this enzyme class is 37341-58-5.

• IUBMB entry for 3.1.3.72

• KEGG entry for 3.1.3.72

• BRENDA entry for 3.1.3.72

• NiceZyme view of 3.1.3.72

• EC2PDB: PDB structures for 3.1.3.72

• PRIAM entry for 3.1.3.72

• PUMA2 entry for 3.1.3.72

• IntEnz: Integrated Enzyme entry for 3.1.3.72

• MetaCyc entry for 3.1.3.72

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050533: 5-phytase

• AMIGO entry for GO code 0050533: 5-phytase