5-Methyltetrahydrofolate
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5-Methyltetrahydrofolate | |
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IUPAC name | (2S)-2-[ [4-[(2-Amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid |
Other names | 5-Methyltetrahydrofolic acid |
Identifiers | |
CAS number | [134-35-0] |
PubChem | |
MeSH | |
SMILES | CN1C(CNC2=C1C(=O)N=C(N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Properties | |
Molecular formula | C20H25N7O6 |
Molar mass | 459.46 g/mol |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
5-Methyltetrahydrofolate, or 5-methyltetrahydrofolic acid, is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).
[edit] See also
- 5-Methyltetrahydrofolate-homocysteine methyltransferase
- S-Adenosyl methionine
- Methylenetetrahydrofolate reductase
- 5,10-Methylenetetrahydrofolate