Talk:5-HT3 antagonist

From Wikipedia, the free encyclopedia

5-HT3 antagonist is part of WikiProject Pharmacology, a project to improve all Pharmacology-related articles. If you would like to help improve this and other pharmacology articles, please join the project. All interested editors are welcome.
B This article has been rated as B-Class on the quality scale.
Top This article has been rated as top-importance for this Project's importance scale.
An entry from 5-HT3 antagonist appeared on Wikipedia's Main Page in the Did you know? column on 22 May 2007.
Wikipedia

Contents

[edit] Cisapride

Cisapride has 5-HT3 antagonist properties (though its primary action is 5-HT4 agonism), should it be included? -- Samir 04:42, 17 May 2007 (UTC)

I thought of that, and renzapride as well, but left it in my sandbox; I couldn't figure out where to place it (at the bottom of the page, perhaps?) Fvasconcellos (t·c) 13:31, 17 May 2007 (UTC)
Noted in the "Available agents" section. I still need to cite it, and you're more than welcome to expand :) Fvasconcellos (t·c) 17:53, 20 May 2007 (UTC)

[edit] EPS with ondansetron?

PMID 12707136 (review) and PMID 12962170. Warrants a closer look at the literature. Fvasconcellos (t·c) 14:15, 24 August 2007 (UTC)

[edit] Generics

A bunch of generic formulations of granisetron have received tentative FDA approval, and will probably reach the market this year. Something to keep an eye on. Fvasconcellos (t·c) 21:56, 23 September 2007 (UTC)

[edit] a few possibilities

I made a couple of minor changes to the article's structure here and there. The article might be getting close to GA, but needs a little more work, I think. The pharmacokinetics section is really too short, though nicely referenced. I think it could be expanded somehow.

I'm not real crazy with the 'available agents' list; I think it's still a little too "listy", though not nearly as bad as some GA nominees I've seen! I'd do away with the bold links of the drug names, as it jumps out at you too strongly. It seems like this could be converted into a 'history' section, which would sort of accomplish two things at once -- listing the various drugs of the class in an easy to see format as well as providing information on the history of development of this class. Dr. Cash 23:54, 26 September 2007 (UTC)

Thank you for your edits. I'm a big fan of definition lists, especially when the section is concise. I could simply change it into "History of available agents"; the list is already in chronological order. It wouldn't be a list anymore, and wouldn't quite be a timeline; I'm not sure this is a great idea—if the content is listy, you may as well make it into a proper list :) I'll reword in my sandbox and see how it can become more proselike. I thought of adding a small table of pharmacokinetic parameters to the PK section. Would that be too much? Fvasconcellos (t·c) 00:19, 27 September 2007 (UTC)

[edit] Other agents

We should chase down information on:

  • Azasetron
  • Bemesetron
  • Ramosetron

There appear to be several others in development. This appears to be an interesting possible source. Fvasconcellos (t·c) 22:42, 1 November 2007 (UTC)