5-dehydro-2-deoxygluconokinase

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In enzymology, a 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92) is an enzyme that catalyzes the chemical reaction

ATP + 5-dehydro-2-deoxy-D-gluconate ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate

Thus, the two substrates of this enzyme are ATP and 5-dehydro-2-deoxy-D-gluconate, whereas its two products are ADP and 6-phospho-5-dehydro-2-deoxy-D-gluconate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase. Other names in common use include 5-keto-2-deoxygluconokinase, 5-keto-2-deoxyglucono kinase (phosphorylating), and DKH kinase. This enzyme participates in inositol metabolism.

[edit] References

• IUBMB entry for 2.7.1.92
• BRENDA references for 2.7.1.92 (Recommended.)
• PubMed references for 2.7.1.92
• PubMed Central references for 2.7.1.92
• Google Scholar references for 2.7.1.92
• Anderson WA, Magasanik B (1971). "The pathway of myo-inositol degradation in Aerobacter aerogenes Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates". J. Biol. Chem. 246: 5662–75. PMID 4328832. 

[edit] External links

The CAS registry number for this enzyme class is 62213-35-8.

• IUBMB entry for 2.7.1.92

• KEGG entry for 2.7.1.92

• BRENDA entry for 2.7.1.92

• NiceZyme view of 2.7.1.92

• EC2PDB: PDB structures for 2.7.1.92

• PRIAM entry for 2.7.1.92

• PUMA2 entry for 2.7.1.92

• IntEnz: Integrated Enzyme entry for 2.7.1.92

• MetaCyc entry for 2.7.1.92

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047590: 5-dehydro-2-deoxygluconokinase

• AMIGO entry for GO code 0047590: 5-dehydro-2-deoxygluconokinase