5-aminopentanamidase

From Wikipedia, the free encyclopedia

In enzymology, a 5-aminopentanamidase (EC 3.5.1.30) is an enzyme that catalyzes the chemical reaction

5-aminopentanamide + H₂O 5-aminopentanoate + NH₃

Thus, the two substrates of this enzyme are 5-aminopentanamide and H₂O, whereas its two products are 5-aminopentanoate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 5-aminopentanamide amidohydrolase. Other names in common use include 5-aminovaleramidase, and 5-aminonorvaleramidase. This enzyme participates in lysine degradation.

[edit] References

• IUBMB entry for 3.5.1.30
• BRENDA references for 3.5.1.30 (Recommended.)
• PubMed references for 3.5.1.30
• PubMed Central references for 3.5.1.30
• Google Scholar references for 3.5.1.30
• Reitz MS, Rodwell VW (1970). "Delta-aminovaleramidase of Pseudomonas putida". J. Biol. Chem. 245: 3091–6. PMID 5432799. 
• Takeda H, Yamamoto S, Kojima Y, Hayaishi O (1969). "Studies on monooxygenases. I. General properties of crystalline L-lysine monooxygenase". J. Biol. Chem. 244: 2935–41. PMID 5772467. 

[edit] External links

The CAS registry number for this enzyme class is 9054-60-8.

• IUBMB entry for 3.5.1.30

• KEGG entry for 3.5.1.30

• BRENDA entry for 3.5.1.30

• NiceZyme view of 3.5.1.30

• EC2PDB: PDB structures for 3.5.1.30

• PRIAM entry for 3.5.1.30

• PUMA2 entry for 3.5.1.30

• IntEnz: Integrated Enzyme entry for 3.5.1.30

• MetaCyc entry for 3.5.1.30

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047588: 5-aminopentanamidase

• AMIGO entry for GO code 0047588: 5-aminopentanamidase