4-oxoproline reductase

From Wikipedia, the free encyclopedia

In enzymology, a 4-oxoproline reductase (EC 1.1.1.104) is an enzyme that catalyzes the chemical reaction

4-hydroxy-L-proline + NAD⁺ 4-oxoproline + NADH + H⁺

Thus, the two substrates of this enzyme are 4-hydroxy-L-proline and NAD⁺, whereas its 3 products are 4-oxoproline, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-hydroxy-L-proline:NAD+ oxidoreductase. This enzyme is also called hydroxy-L-proline oxidase. This enzyme participates in arginine and proline metabolism.

[edit] References

• IUBMB entry for 1.1.1.104
• BRENDA references for 1.1.1.104 (Recommended.)
• PubMed references for 1.1.1.104
• PubMed Central references for 1.1.1.104
• Google Scholar references for 1.1.1.104
• Smith TE and Mitoma C (1962). "Partial purification and some properties of 4-ketoproline reductase". J. Biol. Chem. 237: 1177–1180. 

[edit] External links

The CAS registry number for this enzyme class is 37250-37-6.

• IUBMB entry for 1.1.1.104

• KEGG entry for 1.1.1.104

• BRENDA entry for 1.1.1.104

• NiceZyme view of 1.1.1.104

• EC2PDB: PDB structures for 1.1.1.104

• PRIAM entry for 1.1.1.104

• PUMA2 entry for 1.1.1.104

• IntEnz: Integrated Enzyme entry for 1.1.1.104

• MetaCyc entry for 1.1.1.104

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0016617: 4-oxoproline reductase

• AMIGO entry for GO code 0016617: 4-oxoproline reductase