4-hydroxycyclohexanecarboxylate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a 4-hydroxycyclohexanecarboxylate dehydrogenase (EC 1.1.1.226) is an enzyme that catalyzes the chemical reaction

trans-4-hydroxycyclohexanecarboxylate + NAD⁺ 4-oxocyclohexanecarboxylate + NADH + H⁺

Thus, the two substrates of this enzyme are trans-4-hydroxycyclohexanecarboxylate and NAD⁺, whereas its 3 products are 4-oxocyclohexanecarboxylate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase. This enzyme is also called trans-4-hydroxycyclohexanecarboxylate dehydrogenase.

[edit] References

• IUBMB entry for 1.1.1.226
• BRENDA references for 1.1.1.226 (Recommended.)
• PubMed references for 1.1.1.226
• PubMed Central references for 1.1.1.226
• Google Scholar references for 1.1.1.226
• Obata H, Uebayasi M, Kaneda T (1988). "Purification and properties of 4-hydroxycyclohexanecarboxylate dehydrogenase from Corynebacterium cyclohexanicum". Eur. J. Biochem. 174: 451–8. PMID 3292236. 

[edit] External links

The CAS registry number for this enzyme class is 67272-36-0.

• IUBMB entry for 1.1.1.226

• KEGG entry for 1.1.1.226

• BRENDA entry for 1.1.1.226

• NiceZyme view of 1.1.1.226

• EC2PDB: PDB structures for 1.1.1.226

• PRIAM entry for 1.1.1.226

• PUMA2 entry for 1.1.1.226

• IntEnz: Integrated Enzyme entry for 1.1.1.226

• MetaCyc entry for 1.1.1.226

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047030: 4-hydroxycyclohexanecarboxylate dehydrogenase

• AMIGO entry for GO code 0047030: 4-hydroxycyclohexanecarboxylate dehydrogenase