4-HO-DBT

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4-HO-DBT
Systematic (IUPAC) name
N-butyl-N-[2-(4-hydroxy-1H-indol-3-yl)ethyl]butan-1-amine
Identifiers
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Chemical data
Formula C18H28N2O 
Mol. mass 288.44 g/mol
Physical data
Melt. point 74–75 °C (165–167 °F)
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4-Hydroxydibutyltryptamine (4-HO-DBT) is a psychedelic drug belonging to the tryptamine family. It is found either as its crystalline hydrochloride salt or as an oily or crystalline base. 4-HO-DBT was first made by the chemist Alexander Shulgin and reported in his book TiHKAL. Shulgin reported a dosage of 20mg orally to be without effects. However this compound has subsequently been sold as a "research chemical" and anecdotal reports suggest that at higher doses 4-HO-DBT is indeed an active hallucinogen, although somewhat weaker than other similar tryptamine derivatives.

Several different isomers of this compound could potentially be made (see DBT for a fuller discussion) but of these only the isobutyl isomer 4-HO-DIBT has been synthesised (mp 152-154 °C) and was also found to be inactive at a 20mg dose.

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