4-(dimethylamino)phenylazoxybenzene reductase

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In enzymology, a 4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11) is an enzyme that catalyzes the chemical reaction

4-(dimethylamino)phenylazobenzene + NADP⁺ 4-(dimethylamino)phenylazoxybenzene + NADPH + H⁺

Thus, the two substrates of this enzyme are 4-(dimethylamino)phenylazobenzene and NADP⁺, whereas its 3 products are 4-(dimethylamino)phenylazoxybenzene, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase. Other names in common use include N,N-dimethyl-p-aminoazobenzene oxide reductase, dimethylaminoazobenzene N-oxide reductase, NADPH-dependent DMAB N-oxide reductase, and NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase.

[edit] References

• IUBMB entry for 1.7.1.11
• BRENDA references for 1.7.1.11 (Recommended.)
• PubMed references for 1.7.1.11
• PubMed Central references for 1.7.1.11
• Google Scholar references for 1.7.1.11
• Lashmet Johnson PR, Ziegler DM (1986). "Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol". J. Biochem. Toxicol. 1: 15–27. doi:10.1002/jbt.2570010104. PMID 3152268. 

[edit] External links

The CAS registry number for this enzyme class is 103843-39-6.

• IUBMB entry for 1.7.1.11

• KEGG entry for 1.7.1.11

• BRENDA entry for 1.7.1.11

• NiceZyme view of 1.7.1.11

• EC2PDB: PDB structures for 1.7.1.11

• PRIAM entry for 1.7.1.11

• PUMA2 entry for 1.7.1.11

• IntEnz: Integrated Enzyme entry for 1.7.1.11

• MetaCyc entry for 1.7.1.11

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047136: 4-(dimethylamino)phenylazoxybenzene reductase

• AMIGO entry for GO code 0047136: 4-(dimethylamino)phenylazoxybenzene reductase