3alpha-hydroxyglycyrrhetinate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a 3alpha-hydroxyglycyrrhetinate dehydrogenase (EC 1.1.1.230) is an enzyme that catalyzes the chemical reaction

3alpha-hydroxyglycyrrhetinate + NADP⁺ 3-oxoglycyrrhetinate + NADPH + H⁺

Thus, the two substrates of this enzyme are 3alpha-hydroxyglycyrrhetinate and NADP⁺, whereas its 3 products are 3-oxoglycyrrhetinate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase.

[edit] References

• IUBMB entry for 1.1.1.230
• BRENDA references for 1.1.1.230 (Recommended.)
• PubMed references for 1.1.1.230
• PubMed Central references for 1.1.1.230
• Google Scholar references for 1.1.1.230
• Akao T, Akao T, Hattori M, Namba T, Kobashi K (Tokyo). "Purification and properties of 3 alpha-hydroxyglycyrrhetinate dehydrogenase of Clostridium innocuum from human intestine". J. Biochem.: 504–7. PMID 3164718. 

[edit] External links

The CAS registry number for this enzyme class is 114308-07-5.

• IUBMB entry for 1.1.1.230

• KEGG entry for 1.1.1.230

• BRENDA entry for 1.1.1.230

• NiceZyme view of 1.1.1.230

• EC2PDB: PDB structures for 1.1.1.230

• PRIAM entry for 1.1.1.230

• PUMA2 entry for 1.1.1.230

• IntEnz: Integrated Enzyme entry for 1.1.1.230

• MetaCyc entry for 1.1.1.230

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047032: 3-alpha-hydroxyglycyrrhetinate dehydrogenase

• AMIGO entry for GO code 0047032: 3-alpha-hydroxyglycyrrhetinate dehydrogenase