3'-nucleotidase

From Wikipedia, the free encyclopedia

In enzymology, a 3'-nucleotidase (EC 3.1.3.6) is an enzyme that catalyzes the chemical reaction

a 3'-ribonucleotide + H₂O a ribonucleoside + phosphate

Thus, the two substrates of this enzyme are 3'-ribonucleotide and H₂O, whereas its two products are ribonucleoside and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3'-ribonucleotide phosphohydrolase. Other names in common use include 3'-mononucleotidase, 3'-phosphatase, and 3'-ribonucleotidase. This enzyme participates in purine metabolism and pyrimidine metabolism.

[edit] References

• IUBMB entry for 3.1.3.6
• BRENDA references for 3.1.3.6 (Recommended.)
• PubMed references for 3.1.3.6
• PubMed Central references for 3.1.3.6
• Google Scholar references for 3.1.3.6
• SHUSTER L, KAPLAN NO (1953). "A specific b nucleotidase". J. Biol. Chem. 201: 535–46. PMID 13061389. 

[edit] External links

The CAS registry number for this enzyme class is 9025-84-7.

• IUBMB entry for 3.1.3.6

• KEGG entry for 3.1.3.6

• BRENDA entry for 3.1.3.6

• NiceZyme view of 3.1.3.6

• EC2PDB: PDB structures for 3.1.3.6

• PRIAM entry for 3.1.3.6

• PUMA2 entry for 3.1.3.6

• IntEnz: Integrated Enzyme entry for 3.1.3.6

• MetaCyc entry for 3.1.3.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008254: 3'-nucleotidase

• AMIGO entry for GO code 0008254: 3'-nucleotidase