3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine S-adenosyl-L-homocysteine + (S)-reticuline

Thus, the two substrates of this enzyme are S-adenosyl methionine and 3'-hydroxy-N-methyl-(S)-coclaurine, whereas its two products are S-adenosylhomocysteine and (S)-reticuline.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

[edit] References

• IUBMB entry for 2.1.1.116
• BRENDA references for 2.1.1.116 (Recommended.)
• PubMed references for 2.1.1.116
• PubMed Central references for 2.1.1.116
• Google Scholar references for 2.1.1.116
• Frenzel T, Zenk MH (1990). "S-Adenosyl-L-methionine: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase, a regio- and stereoselective enzyme of the (S)-reticuline pathway". Phytochemistry 29: 3505–3511. doi:10.1016/0031-9422(90)85265-H. 

[edit] External links

The CAS registry number for this enzyme class is 132084-81-2.

• IUBMB entry for 2.1.1.116

• KEGG entry for 2.1.1.116

• BRENDA entry for 2.1.1.116

• NiceZyme view of 2.1.1.116

• EC2PDB: PDB structures for 2.1.1.116

• PRIAM entry for 2.1.1.116

• PUMA2 entry for 2.1.1.116

• IntEnz: Integrated Enzyme entry for 2.1.1.116

• MetaCyc entry for 2.1.1.116

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030784: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase

• AMIGO entry for GO code 0030784: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase