3-oxoacyl-(acyl-carrier-protein) reductase (NADH)

From Wikipedia, the free encyclopedia

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) (EC 1.1.1.212) is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD⁺ 3-oxoacyl-[acyl-carrier-protein] + NADH + H⁺

Thus, the two substrates of this enzyme are [[(3R)-3-hydroxyacyl-[acyl-carrier-protein]]] and NAD⁺, whereas its 3 products are [[3-oxoacyl-[acyl-carrier-protein]]], NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).

[edit] References

• IUBMB entry for 1.1.1.212
• BRENDA references for 1.1.1.212 (Recommended.)
• PubMed references for 1.1.1.212
• PubMed Central references for 1.1.1.212
• Google Scholar references for 1.1.1.212
• Caughey I, Kekwick RG (1982). "The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit". Eur. J. Biochem. 123: 553–61. PMID 7075600. 

[edit] External links

The CAS registry number for this enzyme class is 82047-86-7.

• IUBMB entry for 1.1.1.212

• KEGG entry for 1.1.1.212

• BRENDA entry for 1.1.1.212

• NiceZyme view of 1.1.1.212

• EC2PDB: PDB structures for 1.1.1.212

• PRIAM entry for 1.1.1.212

• PUMA2 entry for 1.1.1.212

• IntEnz: Integrated Enzyme entry for 1.1.1.212

• MetaCyc entry for 1.1.1.212

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047025: 3-oxoacyl-[acyl-carrier-protein reductase (NADH)]

• AMIGO entry for GO code 0047025: 3-oxoacyl-[acyl-carrier-protein reductase (NADH)]