3-methylbutanal reductase

From Wikipedia, the free encyclopedia

In enzymology, a 3-methylbutanal reductase (EC 1.1.1.265) is an enzyme that catalyzes the chemical reaction

3-methylbutanol + NAD(P)+ 3-methylbutanal + NAD(P)H + H⁺

The 3 substrates of this enzyme are 3-methylbutanol, NAD⁺, and NADP⁺, whereas its 4 products are 3-methylbutanal, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methylbutanol:NAD(P)+ oxidoreductase.

[edit] References

• IUBMB entry for 1.1.1.265
• BRENDA references for 1.1.1.265 (Recommended.)
• PubMed references for 1.1.1.265
• PubMed Central references for 1.1.1.265
• Google Scholar references for 1.1.1.265
• van Iersel MF, Eppink MH, van Berkel WJ, Rombouts FM, Abee T (1997). "Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae". Appl. Environ. Microbiol. 63: 4079–82. PMID 9327572. 
• Bertaglia E, Shah D (2005). "Typical atrial flutter ablation and the risk of postablation atrial fibrillation". Ital. Heart. J. 6: 946–9. PMID 16502707. 

[edit] External links

• IUBMB entry for 1.1.1.265

• KEGG entry for 1.1.1.265

• BRENDA entry for 1.1.1.265

• NiceZyme view of 1.1.1.265

• EC2PDB: PDB structures for 1.1.1.265

• PRIAM entry for 1.1.1.265

• PUMA2 entry for 1.1.1.265

• IntEnz: Integrated Enzyme entry for 1.1.1.265

• MetaCyc entry for 1.1.1.265

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0046568: 3-methylbutanal reductase

• AMIGO entry for GO code 0046568: 3-methylbutanal reductase