3-hydroxyaspartate aldolase

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In enzymology, a 3-hydroxyaspartate aldolase (EC 4.1.3.14) is an enzyme that catalyzes the chemical reaction

erythro-3-hydroxy-Ls-aspartate glycine + glyoxylate

Hence, this enzyme has one substrate, erythro-3-hydroxy-Ls-aspartate, and two products, glycine and glyoxylate.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming). Other names in common use include erythro-beta-hydroxyaspartate aldolase, erythro-beta-hydroxyaspartate glycine-lyase, and erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase.

[edit] References

• IUBMB entry for 4.1.3.14
• BRENDA references for 4.1.3.14 (Recommended.)
• PubMed references for 4.1.3.14
• PubMed Central references for 4.1.3.14
• Google Scholar references for 4.1.3.14
• GIBBS RG, MORRIS JG (1964). "ASSAY AND PROPERTIES OF BETA-HYDROXYASPARTATE ALDOLASE FROM MICROCOCCUS DENITRIFICANS". Biochim. Biophys. Acta. 85: 501–3. PMID 14194868. 

[edit] External links

The CAS registry number for this enzyme class is 37290-64-5.

• IUBMB entry for 4.1.3.14

• KEGG entry for 4.1.3.14

• BRENDA entry for 4.1.3.14

• NiceZyme view of 4.1.3.14

• EC2PDB: PDB structures for 4.1.3.14

• PRIAM entry for 4.1.3.14

• PUMA2 entry for 4.1.3.14

• IntEnz: Integrated Enzyme entry for 4.1.3.14

• MetaCyc entry for 4.1.3.14

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047562: 3-hydroxyaspartate aldolase

• AMIGO entry for GO code 0047562: 3-hydroxyaspartate aldolase