3-carboxyethylcatechol 2,3-dioxygenase
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In enzymology, a 3-carboxyethylcatechol 2,3-dioxygenase (EC 1.13.11.16) is an enzyme that catalyzes the chemical reaction
- 3-(2,3-dihydroxyphenyl)propanoate + O2
2-hydroxy-6-oxonona-2,4-diene-1,9-dioate
Thus, the two substrates of this enzyme are 3-(2,3-dihydroxyphenyl)propanoate and O2, whereas its product is 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing). Other names in common use include 2,3-dihydroxy-beta-phenylpropionic dioxygenase, 2,3-dihydroxy-beta-phenylpropionate oxygenase, and 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase. This enzyme participates in phenylalanine metabolism. It employs one cofactor, iron.
[edit] References
- IUBMB entry for 1.13.11.16
- BRENDA references for 1.13.11.16 (Recommended.)
- PubMed references for 1.13.11.16
- PubMed Central references for 1.13.11.16
- Google Scholar references for 1.13.11.16
- Dagley S, Chapman PJ, Gibson DT (1965). "The metabolism of beta-phenylpropionic acid by an Achromobacter". Biochem. J. 97: 643–50. PMID 5881653.
[edit] External links
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- The CAS registry number for this enzyme class is 105503-63-7.
[edit] Gene Ontology (GO) codes
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