2'-deoxymugineic-acid 2'-dioxygenase

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In enzymology, a 2'-deoxymugineic-acid 2'-dioxygenase (EC 1.14.11.24) is an enzyme that catalyzes the chemical reaction

2'-deoxymugineic acid + 2-oxoglutarate + O₂ $\rightleftharpoons$ mugineic acid + succinate + CO₂

The 3 substrates of this enzyme are 2'-deoxymugineic acid, 2-oxoglutarate, and O₂, whereas its 3 products are mugineic acid, succinate, and CO₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The systematic name of this enzyme class is 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating). This enzyme is also called IDS3.

[edit] References

IUBMB entry for 1.14.11.24
BRENDA references for 1.14.11.24 (Recommended.)
PubMed references for 1.14.11.24
PubMed Central references for 1.14.11.24
Google Scholar references for 1.14.11.24
Nakanishi H, Yamaguchi H, Sasakuma T, Nishizawa NK, Mori S (2000). "Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores". Plant. Mol. Biol. 44: 199–207. doi:10.1023/A:1006491521586. PMID 11117263.
Mori S (2001). "In vivo evidence that Ids3 from Hordeum vulgare encodes a dioxygenase that converts 2'-deoxymugineic acid to mugineic acid in transgenic rice". Planta. 212: 864–71. doi:10.1007/s004250000453. PMID 11346963.