2-coumarate O-beta-glucosyltransferase

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In enzymology, a 2-coumarate O-beta-glucosyltransferase (EC 2.4.1.114) is an enzyme that catalyzes the chemical reaction

UDP-glucose + trans-2-hydroxycinnamate $\rightleftharpoons$ UDP + trans-beta-D-glucosyl-2-hydroxycinnamate

Thus, the two substrates of this enzyme are UDP-glucose and trans-2-hydroxycinnamate, whereas its two products are UDP and trans-beta-D-glucosyl-2-hydroxycinnamate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-o-coumarate glucosyltransferase, and UDPG:o-coumaric acid O-glucosyltransferase. This enzyme participates in phenylpropanoid biosynthesis.

[edit] References

IUBMB entry for 2.4.1.114
BRENDA references for 2.4.1.114 (Recommended.)
PubMed references for 2.4.1.114
PubMed Central references for 2.4.1.114
Google Scholar references for 2.4.1.114
Kleinhofs A, Haskins FA and Gorz, HJ (1967). "trans-o-Hydroxylcinnamic acid glucosylation in cell-free extracts of Melilotus alba". Phytochemistry 6: 1313–1318. doi:10.1016/S0031-9422(00)82872-1.
Poulton JE, McRee BE and Conn EE (1980). "Intracellular localization of two enzymes involved in coumarin biosynthesis in Melilotus alba". Plant Physiol. 65: 171–175.