2-aminohexanoate transaminase

From Wikipedia, the free encyclopedia

In enzymology, a 2-aminohexanoate transaminase (EC 2.6.1.67) is an enzyme that catalyzes the chemical reaction

L-2-aminohexanoate + 2-oxoglutarate 2-oxohexanoate + L-glutamate

Thus, the two substrates of this enzyme are L-2-aminohexanoate and 2-oxoglutarate, whereas its two products are 2-oxohexanoate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-2-aminohexanoate:2-oxoglutarate aminotransferase. Other names in common use include norleucine transaminase, norleucine (leucine) aminotransferase, and leucine L-norleucine: 2-oxoglutarate aminotransferase. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 2.6.1.67
• BRENDA references for 2.6.1.67 (Recommended.)
• PubMed references for 2.6.1.67
• PubMed Central references for 2.6.1.67
• Google Scholar references for 2.6.1.67
• Der Garabedian PA, Vermeersch JJ (1987). "Candida L-norleucine,leucine:2-oxoglutarate aminotransferase Purification and properties". Eur. J. Biochem. 167: 141–7. doi:10.1111/j.1432-1033.1987.tb13315.x. PMID 3622507. 

[edit] External links

The CAS registry number for this enzyme class is 111310-35-1.

• IUBMB entry for 2.6.1.67

• KEGG entry for 2.6.1.67

• BRENDA entry for 2.6.1.67

• NiceZyme view of 2.6.1.67

• EC2PDB: PDB structures for 2.6.1.67

• PRIAM entry for 2.6.1.67

• PUMA2 entry for 2.6.1.67

• IntEnz: Integrated Enzyme entry for 2.6.1.67

• MetaCyc entry for 2.6.1.67

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047537: 2-aminohexanoate transaminase

• AMIGO entry for GO code 0047537: 2-aminohexanoate transaminase