2-alkyn-1-ol dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a 2-alkyn-1-ol dehydrogenase (EC 1.1.1.165) is an enzyme that catalyzes the chemical reaction

2-butyne-1,4-diol + NAD⁺ 4-hydroxy-2-butynal + NADH + H⁺

Thus, the two substrates of this enzyme are 2-butyne-1,4-diol and NAD⁺, whereas its 3 products are 4-hydroxy-2-butynal, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-butyne-1,4-diol:NAD+ 1-oxidoreductase.

[edit] References

• IUBMB entry for 1.1.1.165
• BRENDA references for 1.1.1.165 (Recommended.)
• PubMed references for 1.1.1.165
• PubMed Central references for 1.1.1.165
• Google Scholar references for 1.1.1.165
• Miyoshi T, Sato H and Harada T (1974). "Purification and characterization of 2-alkyne-1-ol dehydrogenase induced by 2-butene-1,4-diol in Fusarium merismoides B11". Biochim. Biophys. Acta 358: 231–239. 

[edit] External links

The CAS registry number for this enzyme class is 54576-94-2.

• IUBMB entry for 1.1.1.165

• KEGG entry for 1.1.1.165

• BRENDA entry for 1.1.1.165

• NiceZyme view of 1.1.1.165

• EC2PDB: PDB structures for 1.1.1.165

• PRIAM entry for 1.1.1.165

• PUMA2 entry for 1.1.1.165

• IntEnz: Integrated Enzyme entry for 1.1.1.165

• MetaCyc entry for 1.1.1.165

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047535: 2-alkyn-1-ol dehydrogenase

• AMIGO entry for GO code 0047535: 2-alkyn-1-ol dehydrogenase