2,5-dioxopiperazine hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a 2,5-dioxopiperazine hydrolase (EC 3.5.2.13) is an enzyme that catalyzes the chemical reaction

2,5-dioxopiperazine + H₂O glycylglycine

Thus, the two substrates of this enzyme are 2,5-dioxopiperazine and H₂O, whereas its product is glycylglycine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 2,5-dioxopiperazine amidohydrolase. Other names in common use include cyclo(Gly-Gly) hydrolase, and cyclo(glycylglycine) hydrolase.

[edit] References

• IUBMB entry for 3.5.2.13
• BRENDA references for 3.5.2.13 (Recommended.)
• PubMed references for 3.5.2.13
• PubMed Central references for 3.5.2.13
• Google Scholar references for 3.5.2.13
• Suzuki Y and Uchida K (1985). "Multiple forms of alpha-glycosidase from pig duodenum". Agric. Biol. Chem. 49: 1573–1581. 

[edit] External links

The CAS registry number for this enzyme class is 97599-45-6.

• IUBMB entry for 3.5.2.13

• KEGG entry for 3.5.2.13

• BRENDA entry for 3.5.2.13

• NiceZyme view of 3.5.2.13

• EC2PDB: PDB structures for 3.5.2.13

• PRIAM entry for 3.5.2.13

• PUMA2 entry for 3.5.2.13

• IntEnz: Integrated Enzyme entry for 3.5.2.13

• MetaCyc entry for 3.5.2.13

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047532: 2,5-dioxopiperazine hydrolase

• AMIGO entry for GO code 0047532: 2,5-dioxopiperazine hydrolase