2,4'-dihydroxyacetophenone dioxygenase

From Wikipedia, the free encyclopedia

In enzymology, a 2,4'-dihydroxyacetophenone dioxygenase (EC 1.13.11.41) is an enzyme that catalyzes the chemical reaction

2,4'-dihydroxyacetophenone + O₂ 4-hydroxybenzoate + formate

Thus, the two substrates of this enzyme are 2,4'-dihydroxyacetophenone and O₂, whereas its two products are 4-hydroxybenzoate and formate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is 2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving). This enzyme is also called (4-hydroxybenzoyl)methanol oxygenase. This enzyme participates in bisphenol a degradation.

[edit] References

• IUBMB entry for 1.13.11.41
• BRENDA references for 1.13.11.41 (Recommended.)
• PubMed references for 1.13.11.41
• PubMed Central references for 1.13.11.41
• Google Scholar references for 1.13.11.41
• Hopper DJ (1986). "Oxygenase properties of the (4-hydroxybenzoyl)methanol-cleavage enzyme from an Alcaligenes sp". Biochem. J. 239: 469–72. PMID 3814084. 

[edit] External links

The CAS registry number for this enzyme class is 105503-64-8.

• IUBMB entry for 1.13.11.41

• KEGG entry for 1.13.11.41

• BRENDA entry for 1.13.11.41

• NiceZyme view of 1.13.11.41

• EC2PDB: PDB structures for 1.13.11.41

• PRIAM entry for 1.13.11.41

• PUMA2 entry for 1.13.11.41

• IntEnz: Integrated Enzyme entry for 1.13.11.41

• MetaCyc entry for 1.13.11.41

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047073: 2,4'-dihydroxyacetophenone dioxygenase

• AMIGO entry for GO code 0047073: 2,4'-dihydroxyacetophenone dioxygenase